Computational Biology MCQs with Answer
What is the primary goal of computational biology?
a) Analyzing biological data
b) Conducting laboratory experiments
c) Developing new drugs
d) Engineering biological systems
Correct Answer: a) Analyzing biological data
Which programming language is commonly used in computational biology?
a) Java
b) Python
c) C++
d) MATLAB
Correct Answer: b) Python
What does BLAST stand for in computational biology?
a) Basic Local Alignment Search Tool
b) Biological Language Analysis and Search Technique
c) Biomolecular Localization and Sequence Testing
d) Bioinformatics Link Analysis and Sequence Tool
Correct Answer: a) Basic Local Alignment Search Tool
Which of the following is NOT a common application of computational biology?
a) Protein folding prediction
b) Genome sequencing
c) Weather forecasting
d) Phylogenetic analysis
Correct Answer: c) Weather forecasting
What is the purpose of homology modeling in computational biology?
a) Predicting the structure of proteins
b) Analyzing gene expression
c) Identifying regulatory elements in DNA
d) Designing new drugs
Correct Answer: a) Predicting the structure of proteins
Which algorithm is commonly used for sequence alignment in computational biology?
a) Dijkstra’s algorithm
b) Smith-Waterman algorithm
c) QuickSort algorithm
d) Breadth-first search algorithm
Correct Answer: b) Smith-Waterman algorithm
What is the main objective of phylogenetic analysis in computational biology?
a) Predicting protein structures
b) Identifying evolutionary relationships among species
c) Analyzing gene expression patterns
d) Designing synthetic biological systems
Correct Answer: b) Identifying evolutionary relationships among species
Which of the following is a common database used in computational biology for storing biological data?
a) Spotify
b) PubMed
c) GitHub
d) GenBank
Correct Answer: d) GenBank
What is the purpose of molecular dynamics simulations in computational biology?
a) Analyzing gene expression
b) Predicting protein interactions
c) Designing new drugs
d) Simulating the motion of atoms and molecules over time
Correct Answer: d) Simulating the motion of atoms and molecules over time
Which of the following is NOT a common tool used for protein structure prediction in computational biology?
a) Rosetta
b) PyMOL
c) BLAST
d) Swiss-Model
Correct Answer: c) BLAST
What is the primary goal of genome annotation in computational biology?
a) Predicting the structure of proteins
b) Identifying genes and regulatory elements in DNA sequences
c) Analyzing gene expression patterns
d) Designing new drugs
Correct Answer: b) Identifying genes and regulatory elements in DNA sequences
Which of the following is a common technique for studying gene expression in computational biology?
a) PCR (Polymerase Chain Reaction)
b) Gel electrophoresis
c) Microarray analysis
d) Western blotting
Correct Answer: c) Microarray analysis
What is the purpose of systems biology in computational biology?
a) Analyzing the structure of proteins
b) Studying the interactions between biological components
c) Predicting gene sequences
d) Designing new drugs
Correct Answer: b) Studying the interactions between biological components
Which of the following is a common algorithm used for phylogenetic analysis in computational biology?
a) A* algorithm
b) Maximum likelihood method
c) K-means clustering
d) Random forest algorithm
Correct Answer: b) Maximum likelihood method
What is the primary goal of protein docking in computational biology?
a) Predicting the structure of proteins
b) Analyzing gene expression patterns
c) Studying protein-protein interactions
d) Designing new drugs
Correct Answer: c) Studying protein-protein interactions
Which of the following is a common tool for genome sequencing in computational biology?
a) PCR (Polymerase Chain Reaction)
b) CRISPR-Cas9
c) Sanger sequencing
d) Gel electrophoresis
Correct Answer: c) Sanger sequencing
What is the purpose of comparative genomics in computational biology?
a) Analyzing gene expression patterns
b) Identifying similarities and differences in genomes across different species
c) Predicting protein structures
d) Designing new drugs
Correct Answer: b) Identifying similarities and differences in genomes across different species
Which of the following is a common technique for studying protein-protein interactions in computational biology?
a) X-ray crystallography
b) NMR spectroscopy
c) Yeast two-hybrid system
d) Gel electrophoresis
Correct Answer: c) Yeast two-hybrid system
What is the purpose of gene ontology in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Annotating genes with functional information
d) Designing new drugs
Correct Answer: c) Annotating genes with functional information
Which of the following is a common method for studying protein structure in computational biology?
a) Nucleotide sequencing
b) X-ray crystallography
c) PCR (Polymerase Chain Reaction)
d) Microarray analysis
Correct Answer: b) X-ray crystallography
What is the purpose of RNA-seq in computational biology?
a) Studying gene expression patterns at the DNA level
b) Analyzing protein structures
c) Analyzing gene expression patterns at the RNA level
d) Predicting protein-protein interactions
Correct Answer: c) Analyzing gene expression patterns at the RNA level
Which of the following is a common tool for sequence alignment in computational biology?
a) SPSS
b) ClustalW
c) Excel
d) Photoshop
Correct Answer: b) ClustalW
What is the primary goal of metabolic modeling in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Studying metabolic pathways and networks
d) Designing new drugs
Correct Answer: c) Studying metabolic pathways and networks
Which of the following is a common algorithm used for gene prediction in computational biology?
a) QuickSort algorithm
b) Hidden Markov Model (HMM)
c) Breadth-first search algorithm
d) Support Vector Machine (SVM)
Correct Answer: b) Hidden Markov Model (HMM)
What is the purpose of molecular dynamics simulations in computational biology?
a) Analyzing gene expression
b) Predicting protein interactions
c) Designing new drugs
d) Simulating the motion of atoms and molecules over time
Correct Answer: d) Simulating the motion of atoms and molecules over time
Which of the following is a common technique for studying protein-protein interactions in computational biology?
a) X-ray crystallography
b) NMR spectroscopy
c) Yeast two-hybrid system
d) Gel electrophoresis
Correct Answer: c) Yeast two-hybrid system
What is the purpose of gene ontology in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Annotating genes with functional information
d) Designing new drugs
Correct Answer: c) Annotating genes with functional information
Which of the following is a common method for studying protein structure in computational biology?
a) Nucleotide sequencing
b) X-ray crystallography
c) PCR (Polymerase Chain Reaction)
d) Microarray analysis
Correct Answer: b) X-ray crystallography
What is the purpose of RNA-seq in computational biology?
a) Studying gene expression patterns at the DNA level
b) Analyzing protein structures
c) Analyzing gene expression patterns at the RNA level
d) Predicting protein-protein interactions
Correct Answer: c) Analyzing gene expression patterns at the RNA level
Which of the following is a common tool for sequence alignment in computational biology?
a) SPSS
b) ClustalW
c) Excel
d) Photoshop
Correct Answer: b) ClustalW
What is the primary goal of metabolic modeling in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Studying metabolic pathways and networks
d) Designing new drugs
Correct Answer: c) Studying metabolic pathways and networks
Which of the following is a common algorithm used for gene prediction in computational biology?
a) QuickSort algorithm
b) Hidden Markov Model (HMM)
c) Breadth-first search algorithm
d) Support Vector Machine (SVM)
Correct Answer: b) Hidden Markov Model (HMM)
What is the purpose of molecular dynamics simulations in computational biology?
a) Analyzing gene expression
b) Predicting protein interactions
c) Designing new drugs
d) Simulating the motion of atoms and molecules over time
Correct Answer: d) Simulating the motion of atoms and molecules over time
Which of the following is a common technique for studying protein-protein interactions in computational biology?
a) X-ray crystallography
b) NMR spectroscopy
c) Yeast two-hybrid system
d) Gel electrophoresis
Correct Answer: c) Yeast two-hybrid system
What is the purpose of gene ontology in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Annotating genes with functional information
d) Designing new drugs
Correct Answer: c) Annotating genes with functional information
Which of the following is a common method for studying protein structure in computational biology?
a) Nucleotide sequencing
b) X-ray crystallography
c) PCR (Polymerase Chain Reaction)
d) Microarray analysis
Correct Answer: b) X-ray crystallography
What is the purpose of RNA-seq in computational biology?
a) Studying gene expression patterns at the DNA level
b) Analyzing protein structures
c) Analyzing gene expression patterns at the RNA level
d) Predicting protein-protein interactions
Correct Answer: c) Analyzing gene expression patterns at the RNA level
Which of the following is a common tool for sequence alignment in computational biology?
a) SPSS
b) ClustalW
c) Excel
d) Photoshop
Correct Answer: b) ClustalW
What is the primary goal of metabolic modeling in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Studying metabolic pathways and networks
d) Designing new drugs
Correct Answer: c) Studying metabolic pathways and networks
Which of the following is a common algorithm used for gene prediction in computational biology?
a) QuickSort algorithm
b) Hidden Markov Model (HMM)
c) Breadth-first search algorithm
d) Support Vector Machine (SVM)
Correct Answer: b) Hidden Markov Model (HMM)
What is the purpose of molecular dynamics simulations in computational biology?
a) Analyzing gene expression
b) Predicting protein interactions
c) Designing new drugs
d) Simulating the motion of atoms and molecules over time
Correct Answer: d) Simulating the motion of atoms and molecules over time
Which of the following is a common technique for studying protein-protein interactions in computational biology?
a) X-ray crystallography
b) NMR spectroscopy
c) Yeast two-hybrid system
d) Gel electrophoresis
Correct Answer: c) Yeast two-hybrid system
What is the purpose of gene ontology in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Annotating genes with functional information
d) Designing new drugs
Correct Answer: c) Annotating genes with functional information
Which of the following is a common method for studying protein structure in computational biology?
a) Nucleotide sequencing
b) X-ray crystallography
c) PCR (Polymerase Chain Reaction)
d) Microarray analysis
Correct Answer: b) X-ray crystallography
What is the purpose of RNA-seq in computational biology?
a) Studying gene expression patterns at the DNA level
b) Analyzing protein structures
c) Analyzing gene expression patterns at the RNA level
d) Predicting protein-protein interactions
Correct Answer: c) Analyzing gene expression patterns at the RNA level
Which of the following is a common tool for sequence alignment in computational biology?
a) SPSS
b) ClustalW
c) Excel
d) Photoshop
Correct Answer: b) ClustalW
What is the primary goal of metabolic modeling in computational biology?
a) Analyzing gene expression patterns
b) Predicting protein structures
c) Studying metabolic pathways and networks
d) Designing new drugs
Correct Answer: c) Studying metabolic pathways and networks
Which of the following is a common algorithm used for gene prediction in computational biology?
a) QuickSort algorithm
b) Hidden Markov Model (HMM)
c) Breadth-first search algorithm
d) Support Vector Machine (SVM)
Correct Answer: b) Hidden Markov Model (HMM)
What is the purpose of molecular dynamics simulations in computational biology?
a) Analyzing gene expression
b) Predicting protein interactions
c) Designing new drugs
d) Simulating the motion of atoms and molecules over time
Correct Answer: d) Simulating the motion of atoms and molecules over time
Which of the following is a common technique for studying protein-protein interactions in computational biology?
a) X-ray crystallography
b) NMR spectroscopy
c) Yeast two-hybrid system
d) Gel electrophoresis
Correct Answer: c) Yeast two-hybrid system