Neurobiology of Disease MCQs with Answers
Which of the following is a neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles?
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: c) Alzheimer’s disease
Loss of dopamine-producing cells in the substantia nigra is a hallmark of which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily affected in individuals with depression?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodevelopmental disorder characterized by deficits in social interaction, communication, and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Multiple sclerosis is a disease that affects the:
a) Central nervous system
b) Peripheral nervous system
c) Autonomic nervous system
d) Enteric nervous system
Answer: a) Central nervous system
Which neurotransmitter is associated with motor control and is depleted in individuals with Huntington’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: c) Attention deficit hyperactivity disorder (ADHD)
Which region of the brain is primarily affected in individuals with Alzheimer’s disease?
a) Hippocampus
b) Cerebellum
c) Frontal cortex
d) Occipital lobe
Answer: c) Frontal cortex
Which of the following is a neurodevelopmental disorder characterized by impairments in social interaction, communication, and repetitive behaviors, but with normal language development?
a) Autism spectrum disorder (ASD)
b) Attention deficit hyperactivity disorder (ADHD)
c) Schizophrenia
d) Bipolar disorder
Answer: a) Autism spectrum disorder (ASD)
In individuals with epilepsy, seizures are caused by:
a) Excessive glutamate release
b) Insufficient dopamine production
c) Malfunctioning GABA receptors
d) Abnormal electrical activity in the brain
Answer: d) Abnormal electrical activity in the brain
Which of the following is a neurodegenerative disorder characterized by the progressive loss of motor neurons?
a) Alzheimer’s disease
b) Huntington’s disease
c) Parkinson’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: d) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily associated with reward, motivation, and addiction?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by difficulties in social communication and interaction, as well as restricted and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Loss of myelin sheath in the central nervous system is a characteristic feature of:
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: b) Multiple sclerosis
Which of the following is a neurodegenerative disease characterized by the degeneration of motor neurons, leading to muscle weakness and paralysis?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: c) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily affected in individuals with schizophrenia?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by extreme mood swings that range from depressive episodes to manic episodes?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: b) Bipolar disorder
Which neurotransmitter is primarily associated with mood regulation and is commonly targeted by antidepressant medications?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodegenerative disorder characterized by the loss of coordination, balance, and control over voluntary movements?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: a) Huntington’s disease
Which neurotransmitter is primarily associated with inhibitory signals in the brain and is often targeted in the treatment of anxiety disorders?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: c) GABA
Loss of dopaminergic neurons in the substantia nigra is associated with which neurodegenerative disease?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily associated with learning and memory, and its deficiency is implicated in Alzheimer’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by hallucinations, delusions, and disorganized thinking?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: d) Schizophrenia
Which neurotransmitter is primarily associated with excitatory signals in the brain and is involved in learning and memory?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: d) Glutamate
Which of the following is a neurodegenerative disease characterized by the degeneration of motor neurons and subsequent muscle weakness?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: c) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily associated with muscle movement and is depleted in individuals with Parkinson’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by persistent patterns of inattention, hyperactivity, and impulsivity?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: c) Attention deficit hyperactivity disorder (ADHD)
Loss of GABAergic neurons in the basal ganglia is associated with which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: a) Huntington’s disease
Which neurotransmitter is primarily affected in individuals with anxiety disorders?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: c) Alzheimer’s disease
Which neurotransmitter is primarily associated with muscle movement and is depleted in individuals with Huntington’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by persistent and impairing patterns of inattention, hyperactivity, and impulsivity that interfere with daily functioning?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: c) Attention deficit hyperactivity disorder (ADHD)
Loss of dopaminergic neurons in the basal ganglia is associated with which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily associated with mood regulation and is implicated in mood disorders such as depression and bipolar disorder?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles?
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: c) Alzheimer’s disease
Loss of dopamine-producing cells in the substantia nigra is a hallmark of which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily affected in individuals with depression?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodevelopmental disorder characterized by deficits in social interaction, communication, and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Multiple sclerosis is a disease that affects the:
a) Central nervous system
b) Peripheral nervous system
c) Autonomic nervous system
d) Enteric nervous system
Answer: a) Central nervous system
Which neurotransmitter is associated with motor control and is depleted in individuals with Huntington’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by difficulties in social communication and interaction, as well as restricted and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Loss of myelin sheath in the central nervous system is a characteristic feature of:
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: b) Multiple sclerosis
Which of the following is a neurodegenerative disorder characterized by the progressive loss of motor neurons?
a) Alzheimer’s disease
b) Huntington’s disease
c) Parkinson’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: d) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily associated with reward, motivation, and addiction?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by impairments in social interaction, communication, and repetitive behaviors, but with normal language development?
a) Autism spectrum disorder (ASD)
b) Attention deficit hyperactivity disorder (ADHD)
c) Schizophrenia
d) Bipolar disorder
Answer: a) Autism spectrum disorder (ASD)
In individuals with epilepsy, seizures are caused by:
a) Excessive glutamate release
b) Insufficient dopamine production
c) Malfunctioning GABA receptors
d) Abnormal electrical activity in the brain
Answer: d) Abnormal electrical activity in the brain
Which of the following is a neurodegenerative disorder characterized by the degeneration of motor neurons?
a) Alzheimer’s disease
b) Huntington’s disease
c) Parkinson’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: d) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily associated with mood regulation and is commonly targeted by antidepressant medications?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodegenerative disorder characterized by the loss of coordination, balance, and control over voluntary movements?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: a) Huntington’s disease
Which neurotransmitter is primarily associated with inhibitory signals in the brain and is often targeted in the treatment of anxiety disorders?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: c) GABA
Loss of dopaminergic neurons in the substantia nigra is associated with which neurodegenerative disease?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily associated with learning and memory, and its deficiency is implicated in Alzheimer’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by hallucinations, delusions, and disorganized thinking?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: d) Schizophrenia
Which neurotransmitter is primarily associated with excitatory signals in the brain and is involved in learning and memory?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: d) Glutamate
Which of the following is a neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: c) Alzheimer’s disease
Which neurotransmitter is primarily associated with muscle movement and is depleted in individuals with Parkinson’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by persistent patterns of inattention, hyperactivity, and impulsivity?
a) Autism spectrum disorder (ASD)
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Schizophrenia
Answer: c) Attention deficit hyperactivity disorder (ADHD)
Loss of GABAergic neurons in the basal ganglia is associated with which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Alzheimer’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: a) Huntington’s disease
Which neurotransmitter is primarily affected in individuals with anxiety disorders?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodegenerative disorder characterized by the accumulation of amyloid plaques and neurofibrillary tangles?
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: c) Alzheimer’s disease
Loss of dopamine-producing cells in the substantia nigra is a hallmark of which neurodegenerative disorder?
a) Huntington’s disease
b) Parkinson’s disease
c) Amyotrophic lateral sclerosis (ALS)
d) Multiple sclerosis
Answer: b) Parkinson’s disease
Which neurotransmitter is primarily affected in individuals with depression?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: b) Serotonin
Which of the following is a neurodevelopmental disorder characterized by deficits in social interaction, communication, and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Multiple sclerosis is a disease that affects the:
a) Central nervous system
b) Peripheral nervous system
c) Autonomic nervous system
d) Enteric nervous system
Answer: a) Central nervous system
Which neurotransmitter is associated with motor control and is depleted in individuals with Huntington’s disease?
a) Dopamine
b) Serotonin
c) Acetylcholine
d) Glutamate
Answer: c) Acetylcholine
Which of the following is a neurodevelopmental disorder characterized by difficulties in social communication and interaction, as well as restricted and repetitive behaviors?
a) Schizophrenia
b) Bipolar disorder
c) Attention deficit hyperactivity disorder (ADHD)
d) Autism spectrum disorder (ASD)
Answer: d) Autism spectrum disorder (ASD)
Loss of myelin sheath in the central nervous system is a characteristic feature of:
a) Parkinson’s disease
b) Multiple sclerosis
c) Alzheimer’s disease
d) Huntington’s disease
Answer: b) Multiple sclerosis
Which of the following is a neurodegenerative disorder characterized by the progressive loss of motor neurons?
a) Alzheimer’s disease
b) Huntington’s disease
c) Parkinson’s disease
d) Amyotrophic lateral sclerosis (ALS)
Answer: d) Amyotrophic lateral sclerosis (ALS)
Which neurotransmitter is primarily associated with reward, motivation, and addiction?
a) Dopamine
b) Serotonin
c) GABA
d) Glutamate
Answer: a) Dopamine
Which of the following is a neurodevelopmental disorder characterized by impairments in social interaction, communication, and repetitive behaviors, but with normal language development?
a) Autism spectrum disorder (ASD)
b) Attention deficit hyperactivity disorder (ADHD)
c) Schizophrenia
d) Bipolar disorder
Answer: a) Autism spectrum disorder (ASD)